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Update in infectious diseases in liver transplant recipients

Shirish Huprikar1

  • 1The Mount Sinai Medical Center, Box 1090, One Gustave L Levy Place, New York, NY 10029, USA. shirish.huprikar@mssm.edu

Clinics in Liver Disease
|July 4, 2007
PubMed

Insights

Managing infections in liver transplant recipients is crucial. This review covers updates on bacterial, fungal, and viral infections, including bilomas, peritonitis, and cytomegalovirus disease, plus transplantation in HIV patients.

Area of Science:

  • Hepatology
  • Transplant Surgery
  • Infectious Diseases

Background:

  • Infections pose significant risks to liver transplant recipients.
  • Advances in immunosuppression and prophylaxis have improved outcomes.
  • Persistent challenges necessitate updated management strategies.

Purpose of the Study:

  • To provide current recommendations for managing common infections post-liver transplantation.
  • To review the latest strategies for preventing and treating bacterial, fungal, and viral infections.
  • To discuss the evolving landscape of liver transplantation in human immunodeficiency virus (HIV)-infected individuals.

Main Methods:

  • Review of recent literature and clinical guidelines.
  • Synthesis of evidence on infection management in liver transplant recipients.
  • Analysis of current practices in managing specific infections and patient populations.

Main Results:

  • Updated guidance on managing bilomas and peritonitis.
  • Current approaches to preventing and treating invasive Candida and Aspergillus infections.
  • Strategies for cytomegalovirus (CMV) disease prevention and management.
  • Assessment of outcomes and considerations for liver transplantation in HIV-infected patients.

Conclusions:

  • Effective management of infections remains paramount for successful liver transplantation.
  • Continuous vigilance and adherence to updated guidelines are essential.
  • Liver transplantation is increasingly feasible and successful in carefully selected HIV-infected patients.

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