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Updated: Jul 14, 2026
12:49
Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
Published on: August 17, 2022
Expanding donor options: marginal, living, and split donors
Richard Foster1, Michael Zimmerman, James F Trotter
1Division of Gastroenterology/Hepatology, University of Colorado Health Sciences Center, 4200 E. 9th Avenue, Denver, CO 80262, USA.
Clinics in Liver Disease
|July 4, 2007
Summary
The acceptance of marginal liver grafts, organs with higher risks, is increasing in the US. This trend allows more liver transplantations, including extended criteria donor, split-liver, and living-donor options.
Area of Science:
- Hepatology
- Transplantation Surgery
Background:
- Liver transplantation is crucial for end-stage liver disease.
- Increasing organ demand necessitates the use of marginal grafts.
- Marginal grafts pose higher risks of poor function or failure.
Purpose of the Study:
- To discuss the expanding use of marginal liver grafts in transplantation.
- To review different types of marginal liver grafts and their application.
Main Methods:
- Review of current practices in liver transplantation centers.
- Discussion of extended criteria donor liver transplantation.
- Analysis of split-liver and living-donor liver transplantation techniques.
Main Results:
- Growing acceptance of marginal grafts is observed in the US.
- Broadening criteria for liver transplantation are being adopted.
- Encouraging results support the use of these grafts.
Conclusions:
- Marginal liver grafts are increasingly utilized due to encouraging outcomes.
- Extended criteria donor, split-liver, and living-donor approaches expand transplant options.
- Careful selection and management are key to successful marginal graft transplantation.
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