Related Experiment Video
Updated: Jul 14, 2026

Methods for Detecting Cytotoxic Amyloids Following Infection of Pulmonary Endothelial Cells by Pseudomonas aeruginosa
Published on: July 12, 2018
[Acute rhabdomyolysis during pneumococcal pneumonia: two cases]
H Aouina1, I Aïssa, M A Baccar
1Service de Pneumologie, Hôpital Charles-Nicolle, boulevard du 9-Avril, 1006 Tunis, Tunisie. hichem.aouina@rns.tn
Abstract:
Acute rhabdomyolysis is a clinical and biological syndrome generally with a toxic or traumatic cause. Only 5% of cases are infectious, and rarely in relation to a pneumococcal infection. We report two cases of acute rhabdomyolysis which developed in patients with severe Streptococcus pneumoniae pneumonia. No other cause could be identified in these two patients aged 32 and 37 years. Rhabdomyolysis was discovered in the first patient because of acute kidney failure and elevated serum transaminase levels. The second patient presented an inflammatory edema affecting the soft tissues. Blood cultures isolated a pneumococcus in both patients. The rhabdomyolysis regressed favorably in both patients despite the transient renal failure in the first patient. Prognosis is generally poor for rhabdomyolysis during the course of pneumococcal pneumonia, with increased morbidity and mortality for these infections. Early detection of bacteriemia enables rapid and adequate treatment and prevention of renal failure.
Insights
Severe Streptococcus pneumoniae pneumonia can cause acute rhabdomyolysis, a serious condition. Early detection of pneumococcal bacteremia is crucial for prompt treatment and preventing kidney failure.
Area of Science:
- Infectious Diseases
- Nephrology
- Critical Care Medicine
Background:
- Acute rhabdomyolysis is typically caused by toxins or trauma, with infectious etiologies being rare.
- Streptococcus pneumoniae is an uncommon cause of infectious rhabdomyolysis.
Observation:
- Two cases of severe Streptococcus pneumoniae pneumonia presenting with acute rhabdomyolysis are described.
- Patients, aged 32 and 37, had no other identifiable cause for rhabdomyolysis.
- Clinical manifestations included acute kidney failure, elevated transaminases, and soft tissue edema.
Findings:
- Pneumococcal bacteremia was confirmed in both patients via blood cultures.
- Rhabdomyolysis resolved favorably in both cases, with transient renal impairment in one.
- The study highlights the potential for pneumococcal pneumonia to trigger rhabdomyolysis.
Implications:
- Rhabdomyolysis associated with pneumococcal pneumonia carries a poor prognosis, increasing morbidity and mortality.
- Early identification of bacteremia is vital for timely intervention.
- Prompt treatment can prevent complications such as renal failure.
Related Concept Videos
Atypical Pneumonia
Pneumonia I: Introduction
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia II: Pathophysiology
Acute Pyelonephritis II: Diagnostic Studies and Management
Pneumonia III: Complications and Assessment
