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Inherited factor XI deficiency: a concise review

Massimo Franchini1, Dino Veneri, Giuseppe Lippi

  • 1Servizio di Immunoematologia e Trasfusione - Centro Emofilia, Azienda Ospedaliera di Verona, Italy.

Hematology (Amsterdam, Netherlands)
|July 4, 2007
PubMed

Inherited factor XI (FXI) deficiency, also called Hemophilia C, is an uncommon autosomal recessive disorder, which is associated with a variable bleeding tendency that usually manifests after trauma or surgery. This concise report reviews current knowledge regarding the pathogenesis, genetics, diagnosis, clinical manifestations and management of this inherited bleeding disorder.

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