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Related Experiment Video

Updated: Jul 13, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Treatment goals in psoriasis.

Kristian Reich1, Ulrich Mrowietz

  • 1Dermatologikum Hamburg, Germany. reich@dermatologikum.de

Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
|July 6, 2007
PubMed
Summary

Effective psoriasis treatment requires setting minimum goals, such as a 50% Psoriasis Area and Severity Index (PASI) reduction. If goals aren't met, switch therapies to improve patient quality of life.

Area of Science:

  • Dermatology
  • Immunology
  • Rheumatology

Background:

  • Biologics have expanded psoriasis treatment options, yet many patients experience severe symptoms and low quality of life in Germany.
  • Conventional and biologic therapies for psoriasis are not consistently utilized, potentially impacting treatment outcomes.
  • The German S3 psoriasis guideline offers comprehensive information on treatment efficacy, safety, and practical considerations.

Purpose of the Study:

  • To define minimum treatment goals for psoriasis management.
  • To establish criteria for switching therapies if initial treatment fails to achieve desired outcomes.
  • To emphasize the importance of continuous maintenance therapy and monitoring for psoriatic arthritis and comorbidities.

Main Methods:

  • The study proposes a treatment strategy based on achieving specific clinical targets within a defined timeframe.

Related Experiment Videos

Last Updated: Jul 13, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

  • It recommends a minimum 50% reduction in the Psoriasis Area and Severity Index (PASI) score.
  • A Dermatology Life Quality Index (DLQI) score of less than 5 is suggested as a target for improved quality of life.

    • Main Results:

    • Failure to achieve a 50% PASI reduction or a DLQI score below 5 within a specified period indicates the need for a therapy change.
    • The proposed approach advocates for individualized treatment regimens tailored to patient needs.
    • Continuous maintenance therapy should be implemented as necessary to sustain treatment benefits.

    Conclusions:

    • Setting and monitoring minimum treatment goals are crucial for optimizing psoriasis management.
    • A structured approach to switching therapies ensures patients receive effective treatment.
    • Interdisciplinary collaboration is essential for managing psoriatic arthritis and comorbidities alongside skin symptoms.