An overview on assessing agreement with continuous measurements
Related Experiment Video
Updated: Jul 13, 2026

Doppler Ultrasound-Based Leg Blood Flow Assessment During Single-Leg Knee-Extensor Exercise in an Uncontrolled Setting
Published on: December 15, 2023
Huiman X Barnhart1, Michael J Haber, Lawrence I Lin
1Department of Biostatistics and Bioinformatics and Duke Clinical Research Institute, Duke University, Durham, North Carolina 27715, USA. huiman.barnhart@duke.edu
Abstract:
Reliable and accurate measurements serve as the basis for evaluation in many scientific disciplines. Issues related to reliable and accurate measurement have evolved over many decades, dating back to the nineteenth century and the pioneering work of Galton (1886), Pearson (1896, 1899, 1901), and Fisher (1925). Requiring a new measurement to be identical to the truth is often impractical, either because (1) we are willing to accept a measurement up to some tolerable (or acceptable) error, or (2) the truth is simply not available to us, either because it is not measurable or is only measurable with some degree of error. To deal with issues related to both (1) and (2), a number of concepts, methods, and theories have been developed in various disciplines. Some of these concepts have been used across disciplines, while others have been limited to a particular field but may have potential uses in other disciplines. In this paper, we elucidate and contrast fundamental concepts employed in different disciplines and unite these concepts into one common theme: assessing closeness (agreement) of observations. We focus on assessing agreement with continuous measurements and classify different statistical approaches as (1) descriptive tools; (2) unscaled summary indices based on absolute differences of measurements; and (3) scaled summary indices attaining values between -1 and 1 for various data structures, and for cases with and without a reference. We also identify gaps that require further research and discuss future directions in assessing agreement.
Related Concept Videos
Statistical Analysis: Overview
One of the most commonly used statistical quantifiers is the mean, which is the ratio between the sum of the numerical values of all results and the...
Uncertainty in Measurement: Reading Instruments
Variability: Analysis
The range is a simple measure of variability, indicating the difference between the highest and...
Ratio Level of Measurement
A set of data measured using the ratio scale takes care of the ratio problem and provides complete information. Ratio scale data are like interval scale data, except they have a zero point and ratios can be calculated. For...
Interval Level of Measurement
Data measured using the interval scale are similar to ordinal level data because they have a definite arrangement. However, in the interval level of measurement, the differences between data values are meaningful even though the data does not have a starting point.
Temperature is measured using the interval scale. It is measurable data, and the difference between the...
Accuracy and Precision
