Comparison of concordance correlation coefficient estimating approaches with skewed data
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Updated: Jul 13, 2026

An R-Based Landscape Validation of a Competing Risk Model
Published on: September 16, 2022
Josep L Carrasco1, Lluis Jover, Tonya S King
1Biostatistics, Public Health Department, University of Barcelona, Barcelona, Spain. jlcarrasco@ub.edu
Abstract:
The concordance correlation coefficient (CCC) is an index that assesses the agreement between continuous measures made by different observers. At least four methods are used to estimate the CCC: two (Lin's method, Variance Components) which are defined on the basis that data are normally distributed, and the two others (U-statistics, GEE) which do not assume any particular distribution of the data. Here the four methods are compared with skewed data from a model in which the subject means follow a log-normal distribution while the within-subject variability is assumed to be normally distributed. An example of alcohol consumption is considered and a simulation study is performed.
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