Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fluid restriction during running increases GI permeability.

G P Lambert1, J Lang, A Bull

  • 1Exercise Science and Athletic Training, Creighton University, Omaha, Nebraska 68178, United States. plambert@creighton.edu

International Journal of Sports Medicine
|July 7, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal Testing of Exploratory Behaviour in Mice Reveals Stable Cognitive Traits Across the Adult Lifespan.

Aging cell·2025
Same author

Survey of healthcare-associated sink infrastructure, and sink trap antibiotic residues and biochemistry, in twenty-nine UK hospitals.

The Journal of hospital infection·2025
Same author

Incidence of cervical spine injury in victims of dismounted blast: a systematic review.

BMJ military health·2024
Same author

A workflow for the detection of antibiotic residues, measurement of water chemistry and preservation of hospital sink drain samples for metagenomic sequencing.

The Journal of hospital infection·2023
Same author

Ustekinumab as induction and maintenance therapy for ulcerative colitis - national extended follow-up and a review of the literature.

Expert opinion on drug safety·2023
Same author

Detection, survival, and persistence of Staphylococcus capitis NRCS-A in neonatal units in England.

The Journal of hospital infection·2023
Same journal

Improving assessment of post-exercise hypotension as a predictor of training efficacy.

International journal of sports medicine·2026
Same journal

Neuromuscular electrical stimulation after anterior cruciate ligament reconstruction.

International journal of sports medicine·2026
Same journal

Exercise Intensity Effects on Irisin in Master Athletes and Links With Maximal Oxygen Uptake and Body Fat.

International journal of sports medicine·2026
Same journal

Evolution of the Australian Institute of Sport Supplement Program over the last 25 years.

International journal of sports medicine·2026
Same journal

Preseason Passive Torque Asymmetries in Soccer Players with Hamstring Strain Injury.

International journal of sports medicine·2026
Same journal

Musculoskeletal Burden in German Equestrians: Hip-Specific Symptoms and Risk Factors.

International journal of sports medicine·2026
See all related articles

Fluid restriction during prolonged running significantly increases gastrointestinal permeability. This study found that dehydration elevates both gastroduodenal and intestinal permeability in runners.

Area of Science:

  • Exercise Physiology
  • Gastroenterology
  • Sports Science

Background:

  • Gastrointestinal (GI) distress is common in endurance athletes.
  • Understanding factors affecting GI permeability during exercise is crucial for performance and health.

Purpose of the Study:

  • To investigate the impact of fluid intake on gastrointestinal permeability during prolonged running.
  • To differentiate effects on gastroduodenal versus small intestinal permeability.

Main Methods:

  • Twenty runners underwent four conditions: rest, running with no fluid (NF), glucose solution (GLU), or placebo (PLA).
  • GI permeability assessed using urinary excretion of sucrose (gastroduodenal) and lactulose/rhamnose ratio (small intestine).
  • Dehydration levels monitored via body mass loss.

Related Experiment Videos

Main Results:

  • No significant dehydration occurred in rest, GLU, or PLA conditions.
  • No fluid intake (NF) resulted in 1.5% body mass loss and significantly increased gastroduodenal and intestinal permeability compared to rest.
  • No significant changes in GI permeability were observed in GLU or PLA conditions compared to rest.

Conclusions:

  • Fluid restriction during one hour of steady-state running elevates gastrointestinal permeability.
  • Maintaining hydration is essential to prevent exercise-induced increases in GI permeability.