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Updated: Jul 13, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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Published on: May 28, 2014

Stereochemistry of pladienolide B

Naoki Asai1, Yoshihiko Kotake, Jun Niijima

  • 1Tsukuba Research Laboratories, Eisai Co., Ltd, Tokodai, Tsukuba, Ibaraki, Japan. n2-asai@hhc.eisai.co.jp

The Journal of Antibiotics
|July 10, 2007
PubMed
Summary

Pladienolide B, an antitumor agent from Streptomyces platensis, demonstrates significant potential for cancer treatment. Its precise molecular structure was confirmed using spectral data, paving the way for new drug development.

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