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Infrared irradiation has potential antidepressant effect.

Jui-Feng Tsai1, Sigmund Hsiao, Sin-Yao Wang

  • 1Department of Psychiatry, Buddhist Tzu-Chi General Hospital, Hualien, Taiwan. wccho5255@yahoo.com.tw

Progress in Neuro-Psychopharmacology & Biological Psychiatry
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Summary

Infrared irradiation shows antidepressant effects in mice, significantly reducing depression indicators after four weeks of daily exposure. This suggests continuous infrared therapy may be a viable treatment for depression.

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Area of Science:

  • Neuroscience
  • Biomedical Research

Background:

  • Light therapy offers partial relief for depression compared to natural sunlight.
  • Investigating novel therapeutic modalities for depression is crucial.

Purpose of the Study:

  • To evaluate the antidepressant effect of infrared irradiation.
  • To assess infrared irradiation's impact on depression using an animal model.

Main Methods:

  • Seventeen mice were divided into infrared exposure and control groups.
  • Mice received daily 60-minute infrared irradiation for four weeks.
  • Depression was assessed weekly using the forced swim test and immobility time.

Main Results:

  • A trend towards reduced immobility time was observed by week three in the exposure group.
  • A statistically significant reduction in immobility time was achieved by week four (p = 0.012).

Conclusions:

  • Prolonged infrared irradiation (4 weeks) reduced immobility time, a sign of depression, in the animal model.
  • Continuous infrared irradiation demonstrates antidepressant effects.