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Updated: Jul 13, 2026
07:25
A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Occupational risk factors for prostate cancer
Andrea M Sass-Kortsak1, James T Purdham, Nancy Kreiger
1Department of Public Health Sciences, University of Toronto, Toronto, Canada. a.sass@utoronto.ca
American Journal of Industrial Medicine
|July 11, 2007
Summary
This study found potential links between prostate cancer and whole-body vibration exposure and high workplace physical activity in trades and transport occupations. Further research is recommended.
Area of Science:
- Occupational health
- Epidemiology
- Environmental health
Background:
- Prostate cancer risk factors are inconsistently identified.
- Occupational exposures are a suspected, yet unconfirmed, contributor.
Purpose of the Study:
- To investigate occupational risk factors for prostate cancer.
- To examine associations between specific job types, exposures, and prostate cancer incidence.
Main Methods:
- Population-based case-control study in Northeastern Ontario, Canada.
- Included 760 prostate cancer cases (ages 50-84) and 1,632 controls.
- Assessed occupational history and exposures via questionnaires and expert evaluation.
Main Results:
- Increased odds of prostate cancer linked to "trades, transport and equipment operators" (OR=1.21).
- Whole-body vibration exposure showed a notable association (OR=1.38).
- High lifetime cumulative workplace physical activity also correlated with increased odds (OR=1.33).
Conclusions:
- Limited strong evidence for widespread occupational prostate cancer risks.
- Whole-body vibration and physical activity warrant further investigation as potential occupational factors.
- Highlights need for continued research into environmental and occupational influences on cancer.
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