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Ischemic stroke in patients with diabetic foot
A Pinto1, A Tuttolomondo, D Di Raimondo
1Biomedical Department of Internal and Specialistic Medicine P Giaccone Polyclinic, University of Palermo, Palermo, Italy. pinto@neomedia.it
Summary
Diabetic foot syndrome is linked to a worse cerebrovascular risk profile in type 2 diabetes patients. Those with diabetic foot experienced more cardiovascular risk factors and cerebrovascular events over five years.
Area of Science:
- Endocrinology
- Neurology
- Vascular Medicine
Background:
- Diabetic foot syndrome is a major cause of diabetes-related hospitalization and economic burden.
- Diabetic patients face higher mortality, yet their cerebrovascular risk profile requires further evaluation.
- The role of diabetic foot as a cerebrovascular risk marker in type 2 diabetes is not fully understood.
Purpose of the Study:
- To investigate the potential of diabetic foot as a marker for cerebrovascular risk in type 2 diabetes patients.
- To compare the cerebrovascular risk profiles of type 2 diabetes patients with and without diabetic foot.
Main Methods:
- A cohort of 102 type 2 diabetes patients with diabetic foot and 123 without were enrolled.
- Cardiovascular risk factors and cerebrovascular events were assessed.
- Follow-up occurred over a 5-year period to monitor new-onset cerebrovascular events.
Main Results:
- Significant differences in cardiovascular risk factors (excluding hypertension) were observed between groups.
- Patients with diabetic foot showed a higher prevalence of prior cerebrovascular events (transient ischemic attack, ischemic stroke).
- A higher incidence of new cerebrovascular events was noted in the diabetic foot group over 5 years, with a greater prevalence of lacunar and large artery atherosclerosis stroke subtypes.
Conclusions:
- Diabetic patients with diabetic foot exhibit a poorer cerebrovascular risk profile compared to those without foot ulceration.
- The presence of diabetic foot is associated with increased cardiovascular risk factors and a higher incidence of cerebrovascular events.
- Diabetic foot may serve as an indicator for heightened cerebrovascular risk in type 2 diabetes management.
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