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Related Experiment Video

Updated: Mar 11, 2026

Lexical Decision Task for Studying Written Word Recognition in Adults with and without Dementia or Mild Cognitive Impairment
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Progressive anomia without semantic or phonological impairment.

Janet L Ingles1, John D Fisk, Michael Passmore

  • 1School of Human Communication Disorders, Dalhousie University, Halifax, Canada. janet.ingles@dal.ca

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|July 13, 2007
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Summary

A woman experienced progressive naming difficulties despite intact semantic processing and fluent speech. This unique presentation challenges typical classifications of neurodegenerative language disorders.

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Area of Science:

  • Neuroscience
  • Neurology
  • Linguistics

Background:

  • Neurodegenerative diseases can cause progressive language impairments.
  • Classifications typically include fluent and non-fluent aphasia syndromes.

Observation:

  • A 59-year-old woman presented with profound, progressive naming deficits.
  • Neuroimaging revealed left temporal lobe hypoperfusion (SPECT) and atrophy (MRI).

Findings:

  • The patient exhibited preserved semantic processing and phonological output.
  • Spontaneous speech was fluent with intact syntax and articulation, but significant word-finding difficulties were noted.
  • Other cognitive functions remained stable.

Implications:

  • This case presents atypical features distinct from classic fluent or non-fluent aphasia.
  • Further investigation into the underlying cognitive mechanisms of this specific language impairment is warranted.
  • Understanding such unique presentations can refine diagnostic criteria for neurodegenerative language disorders.