Related Experiment Video
Updated: Jul 13, 2026
Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research
Published on: October 27, 2023
Equivalency study of histological responses to complete or partial pulpotomies in inflamed baboon immature first
P Cleaton-Jones1, M Duggal, R Parak
1University of the Witwatersrand, Dental Research Institute, Johannesburg, South Africa. cleatonjonesp@dentistry.wits.ac.za
Unlabelled:
Partial pulpotomy is an accepted treatment for traumatised incisor teeth with exposed pulps. Clinical studies in humans suggest that this may also be an acceptable technique for carious exposed pulps in molar teeth, but objective histological evidence to support this perception is lacking.
Objective:
To compare histological responses to complete or partial pulpotomies of inflamed pulps in immature baboon first permanent molar teeth.
Methods:
An experimental study in the baboon (Papio ursinus). Pulpitis was induced with fresh Streptococcus mutans placed into occlusal cavities with a small pulpal exposure in 34 first permanent molars of 9 juvenile baboons. After 14 days a pulpotomy, either complete or partial, was performed on the same molars in contra-lateral quadrants using calcium hydroxide covered with IRM and amalgam. After 90 days specimens were harvested and examined under the light microscope with the examiner blind to the treatment.
Results:
Reaction frequencies in the complete and partial pulpotomy teeth were: dentine bridges 9/16 and 10/16, viable pulp in root canals 10/16 and 13/18, peri-apical abscesses 3/13 and 4/13. Fisher's exact probability test showed no statistically significant rates between the groups.
Conclusions:
Complete or partial pulpotomy of inflamed pulps in immature baboon first permanent molars produced comparable reactions.
