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Updated: Jul 13, 2026
A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
Validity of amniotic fluid index in preterm rupture of membranes
Juan Piazze1, Maurizio M Anceschi, Albana Cerekja
1Institute of Gynecology Science, Perinatology and Child Health, University La Sapienza, Rome, Italy. jjpiazze2000@hotmail.com
Background:
Preterm premature rupture of membranes (pPROM) complicates up to one-third of preterm deliveries. We studied the Amniotic Fluid Index (AFI) in order to ascertain its validity as a predictive variable of maternal-fetal outcome in pregnancies complicated by pPROM.
Study Design:
One hundred and fourteen pregnant women with gestational age between 24 and 34 weeks' gestation at the time of pPROM. Patients were categorized into two groups on the basis of AFI value (AFI <5 cm=63 or AFI >or=5 cm=51) performed at the time of admission.
Results:
AFI numeric values were significantly related to the following maternal-neonatal variables: high maternal body temperature (P
Conclusion:
An AFI score <5 cm at admission may be a useful prognostic variable in the management of third trimester pregnancies affected by pPROM.
