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[Tolerance of enteral nutrition in children with acute pancreatitis]
Joanna Kudzin1, Ewa Toporowska-Kowalska, Magdalena Kostrzewska
1Klinika Alergologii, Gastroenterologii i Zywienia Dzieci III Katedry Pediatrii UM, ul. Sporna 36/50, 91-738 Lodz, Poland.
Insights
Enteral nutrition is effective for mild pediatric acute pancreatitis, with most side effects being temporary. However, complications in post-traumatic pancreatitis may reduce tolerance to this nutritional support.
Area of Science:
- Pediatric Gastroenterology
- Clinical Nutrition
- Pancreatology
Background:
- Acute pancreatitis in children is a serious condition requiring effective management.
- Enteral nutrition (EN) is a preferred method for nutritional support in gastrointestinal disorders.
- Assessing the tolerance and efficacy of EN in pediatric acute pancreatitis is crucial for optimizing treatment outcomes.
Purpose of the Study:
- To evaluate the tolerance and efficacy of enteral nutrition in children hospitalized with acute pancreatitis.
- To identify factors influencing the success and potential complications of EN in this patient population.
Main Methods:
- A retrospective analysis of 15 children with 19 episodes of acute pancreatitis treated between 2005-2006.
- Enteral nutrition was administered via nasojejunal catheter using a pump, with a half-elementary/low-fat diet.
- Key parameters assessed included duration of EN, clinical tolerance, caloric intake, and body weight changes.
Main Results:
- Enteral nutrition duration ranged from 3 to 46 days (average 16.15 days).
- Adequate caloric supply (40.46 kcal/kg/day) was achieved, with weight gain in 6 children and weight maintenance in 3.
- Adverse effects (nausea, diarrhea, vomiting) occurred in 47.4% of episodes, mostly transient (31%), requiring nutritional therapy modification in 15.7%.
Conclusions:
- Enteral nutrition is a viable and effective therapy for mild pediatric acute pancreatitis, with generally transient side effects.
- Post-traumatic pancreatitis complications may negatively impact tolerance to enteral nutrition.
- Further research into optimizing EN protocols for different etiologies of pediatric acute pancreatitis is warranted.
Aim:
evaluation of tolerance and efficacy of enteral nutrition inpatients with acute pancreatitis hospitalised in 2005-2006 in Department of Paediatric Allergology, Gastroenterology and Nutrition, Medical University of Lodz.
Material And Methods:
analysis involved the course of enteral nutrition in 15 children hospitalised in 2005-2006 (aged 11.24+/-3.31 year), in whom 19 episodes of acute pancreatitis were observed caused by: trauma (n=4), SPINK1 mutation (n=1, in analysing period 5 episodes was observed in patient) -mutation of serine protease inhibitor Kazal type 1, pancreas divisum (n=1), cholelithiasis (n=1), parasitic AP (n=2), drug-induced (n=3), idiopathic (n=3). 16 episodes were mild and 3 severe (2 pseudocysts and 1 rapture of pancreas). Half-elementary / low-fat diet (Peptisorb / NUTRICIA) was applied by nasojejunal cathether, using pomp (Flocare). Duration, clinical tolerance of enteral nutrition, amount of calories, change of body weight were estimated.
Results:
the length of enteral nutrition varied from 3 to 46 days (average 16.15+/-10.71). The shortest course involved a patient with hereditary acute pancreatitis (average 7.4+/-2.6) the longest one -posttraumatic pancreatitis (average 28.5+/-12.28). By enteral nutrition we ensured the supply of 40.46+/-13.21 kcal/kg per day on average, reaching increase of body weight 733+/-714.23 g in 6 children; maintenance of initial weight in 3 and decrease in 10 patients (average 600+/-534.52 g). Undesirable effects (nausea, diarrhoea, vomitus), observed in 9 episodes of acute pancreatitis (47.4%) were short term in 6 (31%), needed modification of nutritional therapy in 3 (15.7%) (lowering dose of EN in 2, TPN in 1).
Conclusions:
1. Enteral nutrition in children with mild acute pancreatitis is a useful method of therapy and undesirable effects appearing in some patients have transient character. 2. Developing complications in patients with posttraumatic pancreatitis may decrease tolerance to enteral nutrition.
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