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Magnetic resonance imaging as a tool for monitoring stem cell migration
S Magnitsky1, R M Walton, J H Wolfe
1Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.
Abstract:
Noninvasive monitoring of stem cells is an important step in developing stem-cell-based therapies. Among several imaging techniques available, magnetic resonance imaging (MRI) provides an effective way to detect implanted stem cells in live animals. In this mini-review, we discuss the available MRI contrast agents and different cell-labeling strategies used for detection of stem cell migration in the brain. The potential effects of MRI contrast agents on stem cell viability and differentiation are also discussed.

