Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Refractory epilepsy in a Chinese population.

Andrew C F Hui1, Adrian Wong, H C Wong

  • 1Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China. neurologycare@yahoo.com

Clinical Neurology and Neurosurgery
|July 14, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Facilitators and barriers to the implementation of critical care ultrasound (CCUS): an international survey.

Journal of critical care·2026
Same author

Automated data extraction from electronic medical records for pragmatic clinical trials.

Journal of medical systems·2026
Same author

Airway ultrasound in anaesthesia training: a scoping review.

British journal of anaesthesia·2026
Same author

SPOT THE BOT: A comparative quality assessment of AI-generated written instructions for lung ultrasound training.

The ultrasound journal·2026
Same author

Evaluation of Duration of Mechanical Ventilation Associated with Short-Course Midazolam Infusion in the Emergency Department.

The Journal of emergency medicine·2026
Same author

Changes in renal perfusion with brainstem death - revisiting the hypothesis of sympathetically mediated organ hypoperfusion.

Clinical hemorheology and microcirculation·2026

Refractory epilepsy in Chinese adults is often linked to mesial temporal sclerosis and mental retardation. These factors significantly increase the likelihood of developing intractable seizures despite treatment.

Area of Science:

  • Neurology
  • Epileptology
  • Clinical Neuroscience

Background:

  • Epilepsy affects a significant portion of the population, with a subset developing intractable seizures.
  • Understanding risk factors for refractory epilepsy is crucial for improving patient outcomes.

Purpose of the Study:

  • To determine the prevalence of intractable seizures among Chinese patients.
  • To identify risk factors associated with the development of refractory epilepsy in this population.

Main Methods:

  • A cohort of 260 adolescent and adult neurology patients was evaluated.
  • Patients were categorized into refractory epilepsy or seizure-free groups.
  • Logistic regression analysis was used to compare demographic and clinical factors.

Related Experiment Videos

Main Results:

  • 60% of patients achieved complete seizure control.
  • Mesial temporal sclerosis (OR=7.6) and mental retardation (OR=9.39) were significantly associated with pharmacoresistant epilepsy.
  • The underlying etiology was a key factor in seizure control.

Conclusions:

  • The etiology of epilepsy, particularly mesial temporal sclerosis, is a critical determinant of treatment response.
  • Mental retardation is a significant risk factor for developing intractable seizures.
  • These findings highlight specific patient groups requiring targeted management strategies.