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Updated: Jul 13, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Spatial attention and neural asymmetry in obsessive-compulsive disorder
Sari Maril1, Haggai Hermesh, Ruth Gross-Isseroff
1Department of Psychology and Brain and Behavior Center, Haifa University, Israel.
Abstract:
Patterns of lateralized dysfunction in obsessive-compulsive disorder (OCD) were examined using the Posner spatial attention paradigm. While controls responded faster to left visual field targets than to right, patients lacked this asymmetry. The difference in asymmetry patterns was significant for the invalid cue condition, but not for the valid cue condition. Reversal of normal asymmetry was correlated with obsession severity. Findings support aberrant hemispheric balance in OCD.
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