Serotonin-selective reuptake inhibitor-induced enuresis in three pediatric cases

Sabri Hergüner1, Ayşe Kilinçaslan, Işik Görker

  • 1Department of Child and Adolescent Psychiatry, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey. cocukergen@yahoo.com

Insights

Serotonin-selective reuptake inhibitors (SSRIs) can paradoxically cause enuresis (bedwetting) in children. Healthcare providers should monitor pediatric patients for this potential side effect when prescribing SSRIs.

Area of Science:

  • Pediatric medicine
  • Pharmacology
  • Urology

Background:

  • Serotonin-selective reuptake inhibitors (SSRIs) are frequently prescribed for pediatric mental health conditions.
  • While SSRIs are used to treat enuresis, they can also induce it as a side effect.

Observation:

  • This study details three pediatric cases where enuresis developed after initiating SSRI treatment.
  • The onset of enuresis was observed during the course of SSRI therapy in these patients.

Findings:

  • The findings indicate a potential causal link between SSRI use and the development of enuresis in children.
  • These cases highlight that SSRI-induced enuresis is a clinically relevant phenomenon.

Implications:

  • Increased awareness among pediatricians regarding SSRI-induced enuresis is crucial for accurate diagnosis and management.
  • Monitoring for enuresis in children receiving SSRIs is recommended to prevent or address this adverse effect.
  • This underscores the importance of a thorough medication review in pediatric patients presenting with new-onset enuresis.

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