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Published on: October 18, 2021
[Maxillar osteonecrosis associated with bisphosphonate treatment and dental implants]
C Savoldelli1, F Le Page, J Santini
1Service d'ORL et de chirurgie maxillofaciale, hôpital Pasteur, 30, avenue de la Voie-Romaine, 06002 Nice cedex 01, France. csavoldelli@yahoo.fr
Introduction:
Bisphosphosnates are reference products used to treat osteoporosis, malignant bone disease, Paget's disease, and hypercalcemia. However these drugs seem to induce osteonecrosis of the jaws. This osteonecrosis is frequently observed and must be evoked in patients presenting with oral ulceration under bisphosphonate therapy.
Observation:
We report the case of a long-term fully dental implanted patient treated by bisphosphonates who presented a maxillar ostenecrosis with no previous radiotherapy.
Discussion:
The risk factors and mechanism of this induced osteonecrosis are described. But could long term osseo-integrated dental implants be a triggering factor?
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