Related Experiment Video
Updated: Jul 13, 2026

Purification of HLA-G+ Extravillous Trophoblasts from Human Term Placental Tissues for Phenotyping and Functional Analysis
Published on: March 13, 2026
[Severe thrombocytopenic thrombotic purpura and pregnancy: a case report]
M Diop Ndoye1, C Mouloungui, E Diouf
1Service Anesthésie-réanimation, Hôpital Aristide Le Dantec. marie.ndoye@sentoo.sn
Introduction:
Thrombotic thrombocytopenic purpura failure (TTP) is a micro angiopathy caracterized in its severe form by multivisceral involement and early death. The association with pregnancy is rare, the diagnosis is difficult, but imperative because that will allow an early specific management and will improve the diagnosis
Case:
Our patient is a 25 years old woman admitted in intensive care unit after cesarian section for eclampsia at term. Clinical and biological assessement were in favor at Hellp syndrome. Toxemia complicated with eclampsia and Hell syndrome was the final diagnosis and appropriate treatment followed. However the treatment, diffuse purpuric petechia appeared associated with jaundice, thrombocytopenia. The diagnosis of T.T.P was considered and corticotherapy started at day 8. Patient responded within 48 h and healins was complete after 5 weeks.
Conclusion:
Authors emphasized on the importance of the diagnosis and specific management.