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Updated: Jul 13, 2026

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
Published on: November 18, 2018
[Primary arterial pulmonary hypertension and sildenafil: a case report from Dakar]
M Bouldouyre1, D Dia, Fall K Ba
1Service Brevié Hôpital Principal de Dakar.
Introduction:
We report our experience of using sildenafil in treatment on primary arterial pulmonary hypertension.
Patient:
This case concern a 38 years old senegalese woman. She was hospitalised for global cardiac failure with right signs predominance and grade IV dyspnea related to pulmonary hypertension.
Results:
No evident cause of the pulmonary hypertension had been found after explorations. Adding sildénafil to her symptomatic treatment provided fast favourable evolution quantified by clinical test and Doppler-ultrasound heart examination. However the patient died three month later by cerebral hemorrhage due to overdose of antivitamine K.
Conclusion:
We suggest using sildenafil in the treatment of primary arterial pulmonary hypertension on the way going to cardio-pulmonary transplantation.
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