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Updated: Jul 13, 2026

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
[Heart failure: the importance of a disease management program]
Gianna Fabbri1, Marco Gorini, Aldo P Maggioni
1Centro di Coordinamento Registro IN-CHF, Centro Studi ANMCO, Via La Marmora, 34 50121 Firenze.
Frequent hospitalizations significantly impact heart failure patient quality of life and care costs. Multidisciplinary disease management programs show promise in reducing heart failure admissions, though survival benefits remain unclear.
Area of Science:
- Cardiology
- Public Health
- Health Services Research
Context:
- Heart failure (HF) is a growing public health concern with high hospitalization rates, significantly impacting patient quality of life and healthcare costs.
- Existing disease management programs and multidisciplinary approaches aim to reduce HF hospitalizations, as highlighted in recent consensus documents.
- Previous studies on intervention programs show mixed results regarding admission reduction and survival benefits, necessitating further investigation.
Purpose:
- To evaluate the effectiveness of a centralized telephone intervention program for heart failure (HF) patients in reducing hospitalizations and improving outcomes.
- To analyze hospitalization predictors and readmission rates in a large cohort of Italian HF patients using the IN-CHF registry.
- To assess the impact of multidisciplinary care continuity on HF admissions and mortality.
Summary:
- The multicenter randomized DIAL study found that a centralized telephone intervention significantly reduced heart failure admissions but not all-cause admissions or mortality compared to usual care.
- Data from the IN-CHF registry (9000 patients) identified prior HF hospitalization as the strongest predictor of rehospitalization, with 44% hospitalized within the year before enrollment.
- Patients in advanced functional classes (NYHA class III-IV) and with ischemic etiology faced higher rehospitalization rates.
Impact:
- Findings suggest that targeted telephone interventions can effectively decrease HF-specific hospitalizations, offering a potential strategy for managing this chronic condition.
- Identifying high-risk patient groups (e.g., those with prior admissions, advanced NYHA class, ischemic heart disease) allows for focused resource allocation and preventative care.
- The study underscores the significant burden of HF hospitalizations in Italy and the need for effective management strategies to improve patient outcomes and reduce healthcare expenditure.
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