Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chaos and illusion.

J M van Rossum1, J E de Bie

  • 1Department of Pharmacology, Medical Faculty and Faculty of Sciences, Catholic University of Nijmegen, The Netherlands.

Trends in Pharmacological Sciences
|October 1, 1991
PubMed
Summary

Pharmacology research can benefit from chaos theory to understand complex drug effects. Measuring multiple variables simultaneously offers a clearer picture of how drugs impact the human body.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Diagnostics and treatment of suicidality; a matter of customization].

Tijdschrift voor psychiatrie·2024
Same author

The nucleus accumbens of rats and dopaminergic mechanisms regulating locomotor behaviour.

Neuroscience letters·2009
Same author

Psychotropic drug use in a group of Dutch nursing home patients with dementia: many users, long-term use, but low doses.

Pharmacy world & science : PWS·1996
Same author

[Use of psychotropic drugs in a group of nursing home patients with dementia: many users, long-term use but low dosages].

Tijdschrift voor gerontologie en geriatrie·1993
Same author

Sub-50 oral contraceptives affect folate kinetics.

Gynecologic and obstetric investigation·1993
Same author

Interaction of legume lectins with the cellular metabolism of differentiated Caco-2 cells.

Gastroenterology·1992

Area of Science:

  • Pharmacology
  • Nonlinear Dynamics
  • Systems Biology

Background:

  • Pharmacology studies drug interactions with living organisms.
  • Drug effects involve multiple, interrelated, nonlinear variables.
  • Current methods often oversimplify by focusing on single variables.

Purpose of the Study:

  • To explore the application of chaos theory to pharmacological research.
  • To advocate for simultaneous measurement of multiple drug effect variables.
  • To highlight the limitations of traditional, single-variable approaches.

Main Methods:

  • Conceptual analysis integrating chaos theory principles with pharmacology.
  • Discussion of nonlinear system dynamics in biological contexts.
  • Critique of averaging data across populations.

Main Results:

  • Drug effects are inherently complex and nonlinear.
  • Simultaneous measurement of variables is crucial for accurate understanding.
  • Oversimplified models obscure the true nature of drug actions.

Conclusions:

  • Chaos theory offers a valuable framework for modern pharmacology.
  • Adopting nonlinear approaches enhances the understanding of drug-organism interactions.
  • Future research should prioritize multidimensional analysis of drug effects.

Related Experiment Videos