Related Experiment Video

Updated: Oct 23, 2026

An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach
07:13

An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach

Published on: December 7, 2016

[A new method of drug administration into the posterior section of the sub-Tenon's space]

A P Nesterov, S N Basinskiĭ

    Vestnik Oftalmologii
    |September 1, 1991
    PubMed

    More Related Videos

    Intracameral Injection in Rats with Low Risk of Adverse Effects06:19

    Intracameral Injection in Rats with Low Risk of Adverse Effects

    Published on: May 31, 2024

    Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats06:30

    Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats

    Published on: May 23, 2025

    Related Concept Videos

    Routes of Drug Administration: Parenteral01:25

    Routes of Drug Administration: Parenteral

    The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
    The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
    The IV route is often...
    Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

    Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

    Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
    One of the advantages of...
    Drug Delivery: Parenteral Route01:29

    Drug Delivery: Parenteral Route

    The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
    There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
    Drug Delivery: Miscellaneous Routes01:22

    Drug Delivery: Miscellaneous Routes

    Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
    Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
    Transdermal patches transport drugs through the...
    Ophthalmic Drug Delivery Systems01:23

    Ophthalmic Drug Delivery Systems

    Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...