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Updated: Jul 13, 2026

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Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens
Published on: December 9, 2022
Pseudomyxoma peritonei occurring after an uneventful 23 years interval from appendectomy
Atsuko Taii1, Junichi Sakagami, Misumi Shinoda
1Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science. atsuko@koto.kpu-m.ac.jp
Internal Medicine (Tokyo, Japan)
|July 20, 2007
Summary
Pseudomyxoma peritonei, a rare condition, can develop over 20 years after initial treatment. This case highlights the need for long-term patient surveillance for this abdominal malignancy.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- A 77-year-old male presented with a bulky abdominal mass.
- Patient had a history of appendectomy for appendiceal rupture 23 years prior and lung cancer resection 2 years prior.
Observation:
- Initial diagnosis considered peritoneal metastases from lung cancer.
- Patient received chemotherapy without remission.
- Final diagnosis of pseudomyxoma peritonei was confirmed via abdominocentesis.
Findings:
- Pseudomyxoma peritonei was diagnosed after a significant latency period.
- Debulking surgery was performed.
- The patient died 56 days post-surgery.
Implications:
- Pseudomyxoma peritonei necessitates prolonged patient observation due to its potential for late detection.
- This case underscores the importance of considering rare diagnoses even after extensive prior treatments.
- Long-term follow-up is crucial for managing patients with a history suggestive of pseudomyxoma peritonei.
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