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Related Concept Videos

Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
Infertility in Females01:28

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of endometrial...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Spermatogenesis01:41

Spermatogenesis

Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male reproductive...
Menopause01:28

Menopause

Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...

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Related Experiment Video

Updated: Jul 13, 2026

Clinical Anthropometrics and Body Composition from 3-Dimensional Optical Imaging
06:48

Clinical Anthropometrics and Body Composition from 3-Dimensional Optical Imaging

Published on: June 7, 2024

Men's body mass index and infertility.

Ruby H N Nguyen1, Allen J Wilcox, Rolv Skjaerven

  • 1National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH, DHHS), Research Triangle Park, NC, USA. nguyen5@niehs.nih.gov

Human Reproduction (Oxford, England)
|July 20, 2007
PubMed
Summary

Higher body mass in men is linked to increased infertility risk. This association is not explained by changes in sexual function, suggesting weight management may be key for male fertility.

Related Experiment Videos

Last Updated: Jul 13, 2026

Clinical Anthropometrics and Body Composition from 3-Dimensional Optical Imaging
06:48

Clinical Anthropometrics and Body Composition from 3-Dimensional Optical Imaging

Published on: June 7, 2024

Area of Science:

  • Reproductive Health
  • Men's Health
  • Obesity Research

Background:

  • Excess weight in men is potentially linked to hormonal imbalances, reduced semen quality, and infertility.
  • Investigating the relationship between body mass index (BMI) and male infertility is crucial for public health.

Purpose of the Study:

  • To determine if higher BMI in men is associated with infertility.
  • To assess if altered sexual function mediates the relationship between male BMI and infertility.

Main Methods:

  • Retrospective cohort study of 26,303 planned pregnancies from the Norwegian Mother and Child Cohort Study (1999-2005).
  • Infertility defined as taking >or=12 months to conceive or receiving infertility treatment.
  • Data collected via questionnaires on parental height, weight, and time to pregnancy.

Main Results:

  • Overweight (BMI 25-29.9) and obese (BMI 30-34.9) men showed increased odds of infertility (OR=1.20 and 1.36, respectively) compared to men with low-normal BMI (20.0-22.4), after adjusting for confounders.
  • A trend of increased infertility with increasing male BMI was observed across eight BMI categories.
  • The association between male BMI and infertility remained consistent regardless of coital frequency, suggesting it's not mediated by sexual dysfunction.

Conclusions:

  • Excess body weight in men is associated with a higher risk of infertility.
  • The study's findings may underestimate the true impact, as couples who do not conceive are excluded.
  • Further research is recommended to explore the potential benefits of weight loss on male fertility.