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Related Experiment Videos

Swallowing problems in rheumatoid arthritis.

A Geterud1, B Bake, A Bjelle

  • 1Department of Otorhinolaryngology, University of Gothenburg, Sahlgren's Hospital, Sweden.

Acta Oto-Laryngologica
|January 1, 1991
PubMed
Summary

Rheumatoid arthritis (RA) patients frequently experience dry mouth (xerostomia) and swallowing difficulties (dysphagia). RA may cause esophageal muscle dysfunction, contributing to these symptoms.

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Area of Science:

  • Rheumatology
  • Gastroenterology
  • Oral Medicine

Background:

  • Rheumatoid arthritis (RA) is a systemic autoimmune disease.
  • Oral and esophageal symptoms like xerostomia and dysphagia can affect RA patients' quality of life.

Purpose of the Study:

  • To investigate the prevalence of oral symptoms, particularly xerostomia, and swallowing difficulties in rheumatoid arthritis patients.
  • To assess salivary gland function and esophageal motility in RA patients.

Main Methods:

  • A study involving 29 female RA patients and 30 controls.
  • Methods included questionnaires, physical examination, stimulated saliva secretion tests, labial salivary gland biopsy, esophageal manometry, and blood tests.

Main Results:

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  • Xerostomia was reported by 21% of RA patients versus 0% of controls.
  • Dysphagia was reported by 28% of RA patients versus 3% of controls and was associated with disease severity.
  • Esophageal manometry indicated striated muscle dysfunction in RA patients, but no correlation with dysphagia was found.

Conclusions:

  • RA patients exhibit a higher prevalence of xerostomia and dysphagia.
  • Esophageal motility may be impaired in RA patients, suggesting potential systemic effects on muscle function.