Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

WITHDRAWN: Vaccines for preventing anthrax.

T Jefferson, V Demicheli, J Deeks

    The Cochrane Database of Systematic Reviews
    |July 20, 2007
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Viral cultures, cycle threshold values and viral load estimation for assessing SARS-CoV-2 infectiousness in haematopoietic stem cell and solid organ transplant patients: a systematic review.

    The Journal of hospital infection·2022
    Same author

    Viral cultures for assessing fomite transmission of SARS-CoV-2: a systematic review and meta-analysis.

    The Journal of hospital infection·2022
    Same author

    Worldwide surveillance of self-reported sitting time: a scoping review.

    The international journal of behavioral nutrition and physical activity·2020
    Same author

    Evaluation of Swab and Tissue Excision Methods for Recovering Microorganisms from Washed and Sanitized Beef Carcasses <sup>1,</sup> <sup>2</sup>.

    Journal of food protection·2019
    Same author

    A research agenda to guide progress on childhood obesity prevention in Latin America.

    Obesity reviews : an official journal of the International Association for the Study of Obesity·2017
    Same author

    A Comparison of Outcomes in Patients with Infrapopliteal Disease Randomised to Vein Bypass or Plain Balloon Angioplasty in the Bypass vs. Angioplasty in Severe Ischaemia of the Leg (BASIL) Trial.

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2017

    Killed anthrax vaccines are effective in preventing anthrax disease. While some adverse effects were reported, the overall safety profile appears favorable for anthrax vaccination.

    Area of Science:

    • Infectious Diseases
    • Vaccinology
    • Public Health

    Background:

    • Anthrax is a dangerous bacterial illness with severe forms.
    • Current anthrax vaccines' comparative effectiveness and safety are not well-established.

    Purpose of the Study:

    • To evaluate the efficacy and safety of anthrax vaccines.
    • To analyze adverse effects and disease incidence in vaccinated individuals.

    Main Methods:

    • Systematic review of randomized controlled trials (RCTs) and quasi-RCTs.
    • Searched multiple databases including MEDLINE, EMBASE, and Cochrane Library.
    • Assessed trial quality and extracted data on effectiveness and adverse events.

    Main Results:

    • Two trials with 16,052 participants met inclusion criteria, despite methodological limitations.

    Related Experiment Videos

  • Vaccination significantly reduced the risk of contracting anthrax compared to placebo (RR 0.16; 95% CI 0.07 to 0.35).
  • Killed anthrax vaccine showed a higher incidence of adverse effects (POR 5.15; 95% CI 2.28 to 11.61), affecting just over 5% of recipients.

    • Conclusions:

    • Killed anthrax vaccines demonstrate effectiveness in reducing anthrax incidence.
    • Further research is needed on the short- and long-term safety and effectiveness of available anthrax vaccines.