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[Relationship between child day-care attendance and acute infectious disease. A systematic review]
Carlos Ochoa Sangrador1, M Verisima Barajas Sánchez, Beatriz Muñoz Martín
1Servicio de Pediatría, Hospital Virgen de la Concha, Zamora. cochoas@meditex.es
Insights
Child day-care attendance increases the risk of common childhood illnesses like respiratory infections and gastroenteritis. This systematic review quantifies these risks, highlighting significant health implications for young children.
Area of Science:
- Pediatrics
- Epidemiology
- Public Health
Background:
- Child day-care attendance is a known risk factor for early childhood diseases.
- Previous studies have not fully quantified the associated health risks.
Purpose of the Study:
- To systematically review and quantify the health risks associated with child day-care attendance in young children.
- To analyze the impact on various acute childhood infections.
Main Methods:
- Systematic review of clinical trials and cohort studies from Cochrane Collaboration, PubMed, Spanish Medical Index, and EMBASE.
- Methodological quality assessed using personalized criteria.
- Meta-analysis of pooled measures (relative risks, incidence density ratios) with random effects models.
Main Results:
- Child day-care attendance significantly increases the risk of upper respiratory tract infections (RR=1.88), acute otitis media (RR=1.58), otitis media with fluid draining (RR=2.43), lower respiratory tract infections (overall RR=2.10), and gastroenteritis (RR=1.40).
- Day-care attendance may account for 33%-50% of respiratory infection and gastroenteritis episodes in this population.
- Increased risk was consistent across different social and geographical settings.
Conclusions:
- Child day-care attendance presents a discreet but high-impact risk to childhood health.
- Findings have significant implications for clinical practice, public health policy, and future research.
- Evidence supports increased vigilance and potential interventions for healthcare providers and authorities.
Abstract:
Child day-care attendance is considered to be an acute early childhood disease risk factor, the studies available however not affording the possibility of fully quantifying this risk. A systematic review of clinical trials and cohort studies was conducted, in which the effects child day-care attendance had on the health of young children based on the Cochrane Collaboration, PubMed and Spanish Medical Index databases, without any time or language-related limits, were analyzed and rounded out with analyses of referenced works and an additional EMBASE search. The methodological quality was evaluated by means of personalized criteria. Pooling measures (relative risks, incidence density ratios and weighted mean differences) were calculated with their confidence intervals, assuming random effects models. A significant increase was found to exist of a risk consistent over time and among different social and geographical environments. Considering the most methodologically-stringent studies with adjusted effect estimates, child day-care attendance was related to an increased risk of upper respiratory tract infection (RR=1,88), acute otitis media (RR=1,58), otitis media with fluid draining (RR=2,43), lower respiratory tract infections (overall RR=210; acute pneumonia RR=1.70; broncholitis RR=1,80; bronchitis RR=2,10) and gastroenteritis (RR=1,40). Child day-care attendance could be responsible for 33%-50% of the episodes of respiratory infection and gastroenteritis among the exposed population. In conclusion, it can be said that the risk for childhood health attributable to the child day-care attendance is discreet but of high-impact. This information has some major implications for research, clinical practice, healthcare authorities and society as a whole.
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