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Published on: October 12, 2017
Mild external ear malformations and renal tract abnormalities: a meta-analysis
Eduardo Cuestas1, Cecilia Bur, Victoria Bongiovanni
1Department of Pediatrics, Academic Unit Hospital Privado, National University of Córdoba, Argentina. ecuestas@hospitalprivadosa.com.ar
Summary
Infants with mild external ear malformations have a higher risk of urinary tract abnormalities. This meta-analysis confirms a significant association, aiding in decisions about medical imaging for newborns.
Area of Science:
- Pediatric Nephrology
- Clinical Genetics
- Medical Imaging
Background:
- The link between mild external ear malformations and urinary tract anomalies requires further research.
- Prevalence of renal abnormalities in infants with ear malformations is debated, causing confusion regarding imaging guidelines.
- This study addresses the controversy surrounding imaging needs for isolated mild external ear malformations.
Purpose of the Study:
- To assess the association between isolated mild external ear malformations and renal tract abnormalities in infants.
- To provide evidence-based guidance for the medical imaging of infants with specific ear anomalies.
Main Methods:
- A meta-analysis of published case-controlled studies was conducted.
- Data from four relevant studies involving 32,983 infants were analyzed.
- Urinary tract abnormalities were detected via ultrasonography.
Main Results:
- A significant association was found between isolated mild external ear malformations and renal tract abnormalities.
- The odds ratio for renal tract anomalies in affected infants was 1.56 (95% CI 1.25-1.94).
Conclusions:
- The meta-analysis confirms a significant association between renal tract abnormalities and isolated mild external ear malformations.
- Findings support the need for careful consideration of renal tract evaluation in infants with these ear anomalies.
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