Related Experiment Video
Updated: Jul 12, 2026

13:13
Nano-fEM: Protein Localization Using Photo-activated Localization Microscopy and Electron Microscopy
Published on: December 3, 2012
Motor proteins at work for nanotechnology
Martin G L van den Heuvel1, Cees Dekker
1Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, Netherlands.
Summary
Biological motor proteins like kinesin and myosin offer powerful nanoscale tools for artificial applications. While current uses are experimental, these molecular machines present a promising avenue for future nanotechnology development.
Area of Science:
- Biotechnology
- Nanotechnology
- Molecular Biology
Background:
- Biological cells utilize molecular machines for essential mechanical functions.
- Motor proteins, such as kinesin and myosin, are key components driving cellular processes.
Purpose of the Study:
- To review the progress in utilizing biological motor proteins for artificial systems.
- To explore the potential of these biomotors in powering and manipulating nanoscale components.
Main Methods:
- Literature review of studies employing motor proteins in artificial environments.
- Focus on kinesin and myosin biomotors operating on biofilaments.
Main Results:
- Kinesin and myosin have been extensively investigated as active nanoscale components.
- Current applications primarily serve as proof-of-principle demonstrations.
Conclusions:
- A diverse toolkit of biological nanosized motors is readily available.
- Significant opportunities exist for exploring novel applications in nanotechnology and beyond.
Related Concept Videos
Mechanical Protein Functions
Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force.
Mechanical Protein Function
Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force.
Applications Of NMR In Biology
Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
The...
The...
Proteomics
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...

