Related Experiment Video
Updated: Jul 13, 2026

A Rat Model of Tibial Cortex Transverse Transport for the Treatment of Lower Limb Ischemia
Published on: March 6, 2026
[Antioxidant and metabolic therapy of lower limb chronic obliterative arterial disease]
V M Koshkin1, S V Murav'ev, L V Dadova
1Faculty Surgery Clinics, Russian State Medical University, Moscow, Russia.
Abstract:
Metabolic therapy is one of several therapeutic strategies that can be used in patients with lower limb chronic obliterative arterial disease (COAD). Tanakan (EGb76) has demonstrated high efficiency and safety in 9 controlled clinical trials and author's clinical series in patients with lower limb COAD. Improvement with significant increase of pain-free walking distance and beneficial safety profile was observed in all cases. Tanakan (EGb76) is highly effective conventional therapeutic agent for memory and attention disorders, dizziness and balance disturbances in adults and elderly patients. Given a common concomitance of these disorders and lower limb COAD, Tanakan can be recommended as a drug of choice for treatment of chronic obliterative arteriopathy.
Related Concept Videos
Peripheral Artery Disease III: Interprofessional Care
Atherosclerosis III: Management
Atherosclerosis IV: Nursing Management
Peripheral Artery Disease IV: Nursing Management
Peripheral Artery Disease I: Introduction
Peripheral Artery Disease V: Postoperative Nursing Management
