Related Experiment Video
Updated: Jul 13, 2026
05:05
Ultrasound Cyclo Plasty in Eyes with Glaucoma
Published on: January 26, 2018
Central corneal thickness, tonometry, and glaucoma risk--a guide for the perplexed
1Department of Ophthalmology and Vision Sciences, University of California, Davis, CA 95817-2307, USA. jdbrandt@ucdavis.edu
Summary
Central corneal thickness (CCT) confounds eye pressure measurements and independently predicts glaucoma development. This review guides ophthalmologists on integrating CCT into glaucoma patient care.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Corneal Physiology
Background:
- The Ocular Hypertension Treatment Study (OHTS) highlighted central corneal thickness (CCT) as a significant factor in glaucoma assessment.
- CCT influences applanation tonometry readings, potentially leading to misinterpretation of intraocular pressure.
Purpose of the Study:
- To review the current literature on central corneal thickness (CCT).
- To provide practical guidance for ophthalmologists on incorporating CCT measurements into clinical practice for glaucoma management.
Main Methods:
- Literature review of studies investigating central corneal thickness (CCT) and glaucoma.
- Analysis of OHTS findings regarding CCT's role.
Main Results:
- Central corneal thickness (CCT) is an independent predictor of glaucoma development.
- CCT acts as a confounder for applanation tonometry, affecting intraocular pressure measurements.
Conclusions:
- Ophthalmologists need to consider CCT in glaucoma risk assessment.
- Integrating CCT into clinical practice is crucial for accurate glaucoma diagnosis and management.
Related Concept Videos
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
01:27Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
01:28Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...