[Aneurysm of anterior communicating artery associated with type 1 neurofibromatosis]

Neurofibromatosis type 1 (NF-1) is an autosomal dominant, hereditary, neurocutaneous syndrome that may primarily or secondarily, affect different organs or systems of the body including the cardiovascular system. The most common vascular abnormality in patients with NF-1 is renal artery stenosis. The most usual cerebrovascular abnormalities identified in these patients are occlusion and stenosis of major intracranial vessels, aneurysms and arteriovenous malformations.

We report a case of a 35 year-old male with NF-1 who presented with sudden headache and neck stiffness. Computed tomography scan revealed subarachnoid hemorrhage. The cerebral angiography revealed aneurysm of the anterior communicating artery.

Cerebrovascular abnormalities including intracranial aneurysms are found in 2.5 % of patients with neurofibromatosis.