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Related Experiment Videos

Sweat function in the diabetic foot.

Nirmala Markendeya1, V Martina, Anil Mathew

  • 1Department of Dermatology, PSG, Institute of Medical Sciences and Research Centre, Coimbatore.

Indian Journal of Dermatology, Venereology and Leprology
|July 24, 2007
PubMed
Summary
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Diabetic neuropathy can cause foot problems like dryness and fissures. A sweat test can detect early signs of this nerve damage, even with normal sensation, making it a valuable diagnostic tool.

Area of Science:

  • Diabetology
  • Neurology
  • Dermatology

Background:

  • Diabetic neuropathy often manifests early with autonomic dysfunction, affecting sweat patterns and leading to foot dryness and fissuring.
  • Altered sweating is a key indicator of autonomic dysfunction in diabetic patients.
  • Assessing sweat function is crucial for understanding diabetic foot complications.

Purpose of the Study:

  • To evaluate sweat function in the diabetic foot.
  • To determine the relationship between diabetes duration, sensation, fissuring, and sweating.
  • To identify early markers for diabetic neuropathy.

Main Methods:

  • Sweat function was assessed in 30 diabetic patients using Ninhydrin impregnated discs.
  • 28 of the 30 patients exhibited fissuring of the feet.

Related Experiment Videos

  • Sensory perception and duration of diabetes were also considered.

    • Main Results:

    • A significant association was found between foot fissuring and sensation.
    • No statistically significant correlation was observed between diabetes duration and fissuring.
    • Loss of sweating was not significantly correlated with fissuring.
    • 60% of patients showed impaired or absent sweating despite normal sensation.

    Conclusions:

    • While fissuring and reduced sweating are common in diabetic foot complications, their correlation was not statistically significant.
    • Altered sweating, even with normal sensation, suggests the sweat test's utility.
    • The sweat test can serve as an early indicator of diabetic neuropathy.