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Related Concept Videos

Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...

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Related Experiment Video

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A 96 Well Microtiter Plate-based Method for Monitoring Formation and Antifungal Susceptibility Testing of Candida albicans Biofilms
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Relationship between Candida and nocturnal denture wear: quantitative study.

M A Compagnoni1, R F Souza, J Marra

  • 1Department of Dental Materials and Prosthodontics, Araraquara Dental School, São Paulo State University, Araraquara, SP, Brazil. compagno@foar.unesp.br

Journal of Oral Rehabilitation
|July 26, 2007
PubMed
Summary

Continuous overnight denture wear significantly increases Candida yeast in saliva. Removing dentures at night reduces Candida levels, highlighting the importance of oral hygiene for denture wearers.

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Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
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Area of Science:

  • Oral microbiology
  • Prosthodontics
  • Infectious diseases

Background:

  • Candida species are common oral inhabitants, but overgrowth can lead to opportunistic infections.
  • Denture use, especially overnight, may create favorable conditions for Candida colonization.
  • Understanding the impact of nocturnal denture wear on oral microbial load is crucial for patient health.

Purpose of the Study:

  • To investigate the association between wearing complete dentures during sleep and the presence of Candida in saliva.
  • To quantify changes in Candida levels in saliva based on different denture-wearing schedules.

Main Methods:

  • A study involving 24 edentulous volunteers divided into two groups: continuous wear (day and night) and daytime wear only.
  • Saliva samples were collected at multiple time points for both groups, correlating with denture use patterns.
  • Candida colony-forming units (CFU/mL) were measured in saliva samples using microbial cultures.

Main Results:

  • Continuous overnight denture wear (Group I) showed significantly higher Candida counts compared to periods without nighttime wear.
  • Daytime-only denture wear (Group II) demonstrated a significant increase in Candida counts after initiating overnight wear.
  • A significant difference in Candida levels was observed between initial overnight wear and subsequent non-wear periods in both groups.

Conclusions:

  • Continuous denture wear during sleep is significantly linked to increased Candida sp. in saliva.
  • Allowing the oral tissues to rest without dentures at night can help reduce Candida levels.
  • These findings underscore the clinical recommendation for denture removal during sleep to mitigate Candida-related oral issues.