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A new cytotoxic carbazole alkaloid from Clausena excavata
Y H Taufiq-Yap1, T H Peh, G C L Ee
1Department of Chemistry, Universiti Putra Malaysia, Selangor, Malaysia. yap@fsas.upm.edu.my
Natural Product Research
|July 27, 2007
Abstract:
A new carbazole alkaloid, 3-carbomethoxy-2-hydroxy-7-methoxycarbazole, Clausine-TY (1), together with two known carbazole alkaloid, Clausine-H (2) and Clausine-B (3), were isolated from the ethyl acetate extract of the stem bark of the Malaysian Clausena excavata. The structures of these compounds were elucidated by spectroscopic analyses. The new carbazole alkaloid shows significant cytotoxicity against CEM-SS cell line.
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