Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dark shadows of screen: How Dark Tetrad traits, social identity, and binge-watching fuel digital fatigue.

Acta psychologica·2026
Same author

Amino alkyl-alkyl/aryl sulphides (DRDE-07 and analogues) as promising cytoprotectants for sulphur and nitrogen mustards - A review.

Toxicology reports·2025
Same author

Oxygen vacancies mediated enhanced photocatalytic activity of band gap engineered BaSn<sub>1-<i>x</i></sub> Cu <sub><i>x</i></sub> O<sub>3</sub> towards methylene blue degradation under visible and sunlight.

RSC advances·2025
Same author

Exploring workplace spirituality, mindfulness, digital technology, and psychological well-being: A complex interplay in organizational contexts.

Acta psychologica·2024
Same author

Probing the molecular interactions between cholinium-based ionic liquids and insulin aspart: A combined computational and experimental study.

International journal of biological macromolecules·2023
Same author

Spectrophotometric Analysis of Fluoride Concentration in Dentifrices for Children in India.

Journal of pharmacy & bioallied sciences·2022

Related Experiment Video

Updated: Jul 13, 2026

Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery (SALLI) MRI in Rats
08:41

Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery (SALLI) MRI in Rats

Published on: July 19, 2013

Inversion-recovery-prepared SSFP for cardiac-phase-resolved delayed-enhancement MRI.

J S Detsky1, J A Stainsby, R Vijayaraghavan

  • 1Department of Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. jay.detsky@sri.utoronto.ca

Magnetic Resonance in Medicine
|July 27, 2007
PubMed
Summary

A new magnetic resonance imaging technique, inversion-recovery steady-state free precession (IR-SSFP), visualizes myocardial infarction (MI) and wall motion simultaneously. This method improves infarct visualization and offers multiple contrast options in a single breath-hold.

More Related Videos

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

Related Experiment Videos

Last Updated: Jul 13, 2026

Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery (SALLI) MRI in Rats
08:41

Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery (SALLI) MRI in Rats

Published on: July 19, 2013

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

Area of Science:

  • Cardiovascular Imaging
  • Magnetic Resonance Imaging
  • Medical Diagnostics

Background:

  • Delayed-enhancement magnetic resonance imaging (DE-MRI) is crucial for visualizing myocardial infarction (MI).
  • Conventional DE-MRI uses inversion-recovery gradient-echo (IR-GRE) sequences, requiring separate cine acquisitions for wall motion assessment.
  • Accurate inversion time (TI) estimation is critical for IR-GRE to null myocardial signal.

Purpose of the Study:

  • To investigate the utility of a steady-state free precession (SSFP) readout after an inversion pulse for DE-MRI.
  • To optimize a segmented IR-SSFP sequence for improved infarct visualization and simultaneous wall motion assessment.
  • To evaluate the performance of IR-SSFP compared to conventional IR-GRE techniques.

Main Methods:

  • Simulations were conducted to analyze the effects of SSFP readout post-inversion pulse in DE-MRI.
  • A segmented IR-SSFP sequence was developed and optimized based on simulation results.
  • The optimized IR-SSFP sequence was tested in 11 patients, acquiring viability and wall motion images within a single breath-hold.

Main Results:

  • The IR-SSFP sequence successfully generated viability images with multiple effective TIs, offering varied contrast.
  • Simultaneous visualization of myocardial viability and wall motion was achieved in a single breath-hold.
  • IR-SSFP demonstrated comparable infarct sizes and left ventricular ejection fractions (LVEFs) to IR-GRE and standard SSFP, respectively.
  • Improved visualization of the infarct-blood border was observed due to simultaneous nulling of healthy myocardium and blood.
  • Extracted T(1) (*) recovery curves from IR-SSFP images showed strong qualitative agreement with theoretical simulations.

Conclusions:

  • The optimized IR-SSFP sequence provides a single-breath-hold method for simultaneous myocardial viability and wall motion assessment.
  • IR-SSFP enhances the visualization of the infarct-blood border, offering diagnostic advantages.
  • This novel sequence shows promise for more efficient and comprehensive cardiac MRI assessments of MI.