Related Experiment Video
Updated: Jul 13, 2026

07:26
Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
Changes in third molar and nonthird molar periodontal pathology over time
George H Blakey1, Donald J Hull, Richard H Haug
1Department of Oral and Maxillofacial Surgery, School of Dentistry, University of North Carolina, Chapel Hill, NC 27599, USA.
Summary
Periodontal probing depth (PD) worsened in non-third molar regions of young adults over time. This progression was more likely if initial PD measurements in the third molar region were 4 mm or greater.
Area of Science:
- Periodontology
- Dental Public Health
- Longitudinal Oral Health Studies
Background:
- Third molars (wisdom teeth) are often associated with periodontal concerns.
- Understanding periodontal changes in young adults is crucial for long-term oral health.
- Longitudinal data on periodontal probing depth (PD) in different tooth regions are limited.
Purpose of the Study:
- To evaluate changes in periodontal probing depth (PD) over time in young adults.
- To compare PD changes between third molar and non-third molar regions.
- To identify risk factors associated with periodontal pathology progression.
Main Methods:
- A longitudinal study involving healthy young adults with four asymptomatic third molars.
- Periodontal probing depth (PD) was measured at baseline and longest follow-up (median 5.9 years).
- Third molar regions included sites around third molars and distal of second molars; non-third molar regions included all other sites.
Main Results:
- The proportion of subjects with involved non-third molar sites (PD ≥ 4 mm) increased significantly from 36% to 49% (P < .01).
- This increase was primarily observed in mandibular non-third molar regions (33% to 48%, P < .01).
- Subjects with baseline PD ≥ 4 mm in the third molar region showed a significant increase in non-third molar involvement (48% to 59%, P = .05).
Conclusions:
- Periodontal pathology demonstrably worsened over time in the non-third molar regions of young adults.
- The presence of periodontal probing depth (PD) ≥ 4 mm in the third molar region was a significant predictor of worsening pathology in non-third molar areas.
- Early detection and monitoring of periodontal health in young adults, particularly around third molars, are essential.
