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Urinary Bladder Botryoid Rhabdomyosarcoma with Immature Cartilage in a 24-year-old Male Patient: A Case Report
Ahlam Al-Shedoukhy1, Azhar Qayyum
1Department of Pathology (32), King Khalid University Hospital, Riyadh, Saudi Arabia.
Summary
This study details a rare adult case of botryoid rhabdomyosarcoma in the urinary bladder. The tumor exhibited unusual cartilaginous differentiation, a feature previously unreported in this location.
Area of Science:
- Uropathology
- Skeletal Muscle Neoplasms
- Tumor Differentiation
Background:
- Botryoid rhabdomyosarcoma is a rare subtype of rhabdomyosarcoma.
- Cartilaginous differentiation is an uncommon feature in rhabdomyosarcomas.
- Previous reports of cartilaginous differentiation in rhabdomyosarcoma have been limited to the uterine cervix.
Purpose of the Study:
- To report a unique case of botryoid rhabdomyosarcoma with cartilaginous differentiation.
- To highlight the occurrence of this rare tumor in the urinary bladder of an adult.
- To contribute to the understanding of rhabdomyosarcoma heterogeneity.
Main Methods:
- Histopathological examination of the tumor.
- Immunohistochemical analysis to confirm the diagnosis.
- Review of relevant literature.
Main Results:
- The tumor displayed characteristic histological and immunohistochemical features of botryoid rhabdomyosarcoma.
- Foci of immature cartilage were identified within the tumor.
- This represents the first reported instance of botryoid rhabdomyosarcoma with cartilaginous differentiation in an adult urinary bladder.
Conclusions:
- Botryoid rhabdomyosarcoma can occur in the urinary bladder of adults.
- Cartilaginous differentiation, though rare, can be a feature of botryoid rhabdomyosarcoma in this location.
- This case expands the known spectrum of rhabdomyosarcoma presentation and differentiation.
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