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Updated: Jan 9, 2026

Modified Laparoscopic Anatomic Hepatectomy: Two-Surgeon Technique Combined with the Simple Extracorporeal Pringle Maneuver
Published on: June 16, 2023
Use of topical hemostatic agents during liver resection
Frederik Berrevoet1, Bernard de Hemptinne
1Department of General Surgery, Division of Hepatobiliary Surgery and Liver Transplantation Service, Ghent University Hospital Medical School, Ghent, Belgium. Frederik.Berrevoet@Ugent.be
Abstract:
Despite all recent developments in surgical techniques during liver surgery, blood loss is still one of the main causes for postoperative morbidity and mortality. Other complications include bile leakage and fluid accumulation intraperitoneally. Fibrin sealants are able not only to enhance clot formation and wound healing but possibly work as a sealing device for postoperative leakage and fistula formation. In this overview the underlying mechanisms for these agents are discussed and several clinical data concerning liver surgery will be reported.
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