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[Plummer Vinson syndrome].

Olfa Ben Gamra1, Chiraz Mbarek, Chaieb Mouna

  • 1Service ORL & Chirurgie cervico-faciale de l'Hôpital Habib Thameur Tunis, Tunisie.

La Tunisie Medicale
|July 31, 2007
PubMed
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Plummer Vinson syndrome, a rare condition in women, presents with dysphagia and iron deficiency. Treatment involves iron supplementation and endoscopic esophageal web intervention, with most patients showing positive outcomes.

Area of Science:

  • Gastroenterology
  • Hematology
  • Otolaryngology

Context:

  • Plummer Vinson syndrome is a rare disorder predominantly affecting white women.
  • Characterized by dysphagia, iron deficiency anemia, and superior esophageal webs.

Purpose:

  • To delineate the epidemiological, clinical, paraclinical, and therapeutic aspects of Plummer Vinson syndrome.
  • To provide a comprehensive overview of this rare condition.

Summary:

  • A 15-year study of 19 Plummer Vinson syndrome cases revealed dysphagia in 100% and anemia in 89.4%.
  • Treatment included iron supplementation and endoscopic esophageal web management (dilatation/rupture).
  • Favorable outcomes were observed in 15 patients, with one case of malignancy.

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Impact:

  • Highlights the importance of early diagnosis and management of Plummer Vinson syndrome.
  • Emphasizes the efficacy of combined iron therapy and endoscopic intervention.
  • Contributes to understanding the long-term prognosis and potential complications, including malignancy.