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Primitive neuroectodermal tumor of the myometrium with cardio-vascular symptoms
Olivier Mir1, Laurence Albiges, Sylviane Arkwright
1Department of Oncology, Assistance Publique - Hôpitaux de Paris, Hôpital Cochin, University Paris 5, Faculty of Medicine, Paris, France. olivier.mir@cch.aphp.fr
Background:
Non-bacterial thrombotic endocarditis is a severe complication of cancer, rarely reported in gynecologic tumors. However, it can be inaugural and lead to complex diagnostic pathways.
Case:
A 40-year-old woman presented with a stroke, related to an endocarditis. The valvular vegetation was surgically removed, and a malignant node was resected. A PET-scan led to the diagnosis of a myometrial tumor, which was found to be a primitive neuroectodermal tumor (PNET). The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, and systemic chemotherapy which allowed a complete remission of tumoral and cardio-vascular symptoms.
Conclusion:
To our knowledge, this is the first case report of a PNET of the myometrium revealed by cardio-vascular symptoms.
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