In vivo 13 carbon metabolic imaging at 3T with hyperpolarized 13C-1-pyruvate

S J Kohler1, Y Yen1, J Wolber2

  • 1GE Healthcare, Menlo Park, California, USA.

Summary

This study introduces dynamic nuclear polarization (DNP) enhanced (13)C-pyruvate MRI in rats, visualizing metabolic conversion into lactate, alanine, and bicarbonate in vivo. The method reveals metabolite distribution across tissues with high temporal and spatial resolution.

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