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Intracranial mycotic aneurysm due to Aspergillus species

C Sundaram1, Deepa Goel, Shantveer G Uppin

  • 1Department of Pathology, Nizam's Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India. challa_sundaram@yahoo.com

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|July 31, 2007
PubMed
Abstract

Insights

Intracranial true mycotic aneurysms are rare and often fatal. Early diagnosis and treatment are crucial for improving outcomes in these challenging Aspergillus-related infections.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Vascular Surgery

Background:

  • Intracranial true mycotic aneurysms are rare, often fatal vascular complications.
  • Aspergillus species are an uncommon but serious cause of these aneurysms, particularly post-surgery.
  • Previous literature review (1990-2005) highlights limited understanding of etiology and outcomes.

Observation:

  • Two cases of basilar mycotic aneurysms caused by Aspergillus species are presented.
  • Both patients experienced subarachnoid hemorrhage following surgical interventions.
  • Diagnosis was only confirmed post-mortem in both reported cases.

Findings:

  • Review of literature from 1990-2005 on intracranial mycotic aneurysms.
  • Etiology, clinical presentation, predisposing factors, and outcomes were analyzed.
  • Aspergillus species identified as a causative agent in post-surgical cases.

Implications:

  • A high index of clinical suspicion is vital for early detection.
  • Prompt diagnosis and timely intervention are critical for potentially improving patient outcomes.
  • Further research is needed to enhance diagnostic and therapeutic strategies for these rare conditions.

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