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Updated: Jul 13, 2026

Erosion Identification in Metacarpophalangeal Joints in Rheumatoid Arthritis using High-Resolution Peripheral Quantitative Computed Tomography
Published on: October 6, 2023
[Pathologic condition of osteoporosis in rheumatoid arthritis]
Akira Suwa1, Eiko Saito, Takayuki Wakabayashi
1Tokai University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Japan.
Abstract:
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic synovitis which causes osteoporosis and joint destruction. Recently, it has been well understood that pro-inflammatory cytokine plays a pivotal role in disease progression. These pro-inflammatory cytokine induces activation of osteoclasts, resulting in paraarticular osteoporosis and joint destruction. While systemic osteoporosis caused by several factors is often seen in patients with RA. This article reviews the pathologic condition of osteoporosis in RA.
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