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[Effect of isoflurane on muscle relaxation in a patient with myotonic dystrophy]
H Komatsu1, T Horiguchi, K Enzan
1Department of Anesthesiology, Akita University School of Medicine.
Abstract:
We did anesthetic management by isoflurane for total thyroidectomy under the neuromuscular transmission monitoring in a patient with myotonic dystrophy. In three patients without neuromuscular disorders, T1 was 85% of control and fade was not observed, while in this case T1 was 40% of the control and TOFR was decreased to 50%. We conclude that isoflurane has a good muscle relaxation effect in this disease and, we could manage without administering any muscle relaxants.