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Related Experiment Video

Updated: Jul 13, 2026

An In-House-Built and Light-Emitting-Diode-Based Photodynamic Therapy Device for Enhancing Verteporfin Cytotoxicity in a 2D Cell Culture Model

An In-House-Built and Light-Emitting-Diode-Based Photodynamic Therapy Device for Enhancing Verteporfin Cytotoxicity in a 2D Cell Culture Model

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[Photodynamic therapy: new indications].

M Fernández-Guarino¹, I García-Morales, A Harto

¹Servicio de Dermatología, Hospital Universitario Ramón y Cajal, Universidad de Alcalá de Henares, Madrid, España. montsefdez@msn.com

Actas Dermo-Sifiliograficas

|August 1, 2007

Summary

Photodynamic therapy (PDT) effectively treats various skin conditions beyond non-melanoma skin cancer, including psoriasis and acne. This review details PDT

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An In-House-Built and Light-Emitting-Diode-Based Photodynamic Therapy Device for Enhancing Verteporfin Cytotoxicity in a 2D Cell Culture Model

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Development of an Innovative LED-based Illumination Device for In Vitro Application of Photodynamic Therapy with Rose Bengal

Development of an Innovative LED-based Illumination Device for In Vitro Application of Photodynamic Therapy with Rose Bengal

Published on: September 12, 2025

Area of Science:

Dermatology and Photomedicine
Oncology
Immunology

Context:

Photodynamic therapy (PDT) is an established treatment for actinic keratoses, basal cell carcinomas, and Bowen's disease.
Recent advancements in photodynamic reactions have broadened PDT's application to diverse cutaneous conditions.
Growing evidence supports PDT for inflammatory and infectious dermatoses.

Purpose:

To review the current applications of photodynamic therapy (PDT) in treating Bowen's disease.
To explore and present clinical experience with PDT for non-melanoma skin cancers and other dermatological conditions.
To evaluate the efficacy of PDT using various photosensitizers and light sources.

Summary:

Photodynamic therapy (PDT) is approved for specific skin cancers and is increasingly used for other conditions like psoriasis, acne, warts, and cutaneous T-cell lymphoma.
The review covers PDT's application in Bowen's disease and other indications beyond non-melanoma skin cancer.
Clinical experience with PDT for a range of dermatoses is provided, highlighting variable results with different treatment parameters.

Impact:

Expands the therapeutic armamentarium for dermatologists.
Offers new treatment options for patients with challenging skin diseases.
Highlights the potential of photodynamic therapy in managing a wider spectrum of cutaneous disorders.